PyeonLab

2024

The membrane-associated ubiquitin ligase MARCHF8 stabilizes the human papillomavirus oncoprotein E7 by degrading CUL1 and UBE2L3 in head and neck cancer

Khalil MI, Vu L, Yang C, Chadha S, Nabors H, James CD, Morgan IM, Pyeon D. Journal of Virology. 2024 Feb 20;98(2):e0172623. doi: 10.1128/jvi.01726-23. PMID: 38226814.

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The Chemokine CXCL14 as a Potential Immunotherapeutic Agent for Cancer Therapy

Giacobbi NS, Mullapudi S, Nabors H, Pyeon D. Viruses. 2024 Feb 16;16(2). doi: 10.3390/v16020302. PMID: 38400076.

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Inducing Long Lasting B Cell and T Cell Immunity Against Multiple Variants of SARS-CoV-2 Through Mutant Bacteriophage Qβ-Receptor Binding Domain Conjugate

Tan Z, Yang C, Lin P, Ramadan S, Yang W, Rashidi Z, Lang S, Shafieichaharberoud F, Gao J, Soloff N, Wu X, Bolin S, Pyeon D, Huang X. Advanced Healthcare Materials. 2024, 11:e2302755. doi: 10.1002/adhm.202302755. Online ahead of print. PMID: 38733291.

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2023

Special Issue "New Frontiers in Small DNA Virus Research"

Strati K, Pyeon D. Viruses 2023, 15, 259. https://doi.org/10.3390/v15010259. PMID: 36680299.

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Virology under the Microscope-a Call for Rational Discourse

Goodrum F, et al. mBio. 2023 Jan 26:e0018823. doi: 10.1128/mbio.00188-23. PMID: 36700642.

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Virology under the Microscope-a Call for Rational Discourse

Goodrum F, et al. Journal of Virology. 2023 Feb 28;97(2):e0008923. doi: 10.1128/jvi.00089-23. Epub 2023 Jan 26. PMID: 36700640.

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Virology under the Microscope-a Call for Rational Discourse

Goodrum F, et al. mSphere. 2023 Apr 20;8(2):e0003423. doi: 10.1128/msphere.00034-23. Epub 2023 Jan 26. PMID: 36700653.

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HPV upregulates MARCHF8 ubiquitin ligase and inhibits apoptosis by degrading the death receptors in head and neck cancer

Khalil MI, Yang C, Vu L, Chadha S, Nabors H. Welbon C, James CD, Morgan IM, Spanos WC, Pyeon D. PLoS Pathogens. 2023 Mar;19(3):e1011171. doi: 10.1371/journal.ppat.1011171. PMID: 36867660.

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2022

APOBEC3: Friend or Foe in Human Papillomavirus Infection and Oncogenesis?

Warren CJ, Santiago ML, Pyeon D. Annual Review of Virology. 2022, doi: 10.1146/annurev-virology-092920-030354. PMID: 35671565.

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Rational Design and Synthesis of D-galactosyl Lysophospholipids as Selective Substrates and non-ATP-competitive Inhibitors of Phosphatidylinositol Phosphate Kinases

Sun M, Zhang C, Sui D, Yang C, Pyeon D, Huang X, Hu J. Chemistry. 2022 Nov 24:e202202083. doi: 10.1002/chem.202202083. PMID: 36424188.

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Inducing long lasting B cell and T cell immunity against multiple variants of SARS-CoV-2 through mutant bacteriophage Qβ – receptor binding domain conjugate

Tan Z, Yang C, Lin P, Ramadan S, Yang W, Rashidi Z, Lang S, Shafieichaharberoud F, Gao J, Soloff N, Wu X, Bolin S, Pyeon D, Huang X. 2022, ChemRxiv. 10.26434/chemrxiv-2022-rdk8m.

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2021

The Key Differences between Human Papillomavirus-Positive and -Negative Head and Neck Cancers: Biological and Clinical Implications

Powell S, Vu L, Spanos WC, Pyeon D. Cancers. 2021, 13(20): 5206. PMID: 34680354.

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2020

The multifarious roles of the chemokine CXCL14 in cancer progression and immune responses

Westrich JA, Vermeer DW, Colbert PL, Spanos WC, Pyeon D. Molecular Carcinogenesis. 2020 Jul;59(7):794-806. PMID: 32212206. (Top Cited Articles, 2020-2021)

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The antiviral immune forces awaken in the cancer wars

Pyeon D, Vu L, Giacobbi NS, Westrich JA. PLoS Pathogens. 2020 Sep 3;16(9):e1008814. PMID: 32881981.

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2019

CXCL14 suppresses human papillomavirus-associated head and neck cancer through antigen-specific CD8+ T-cell responses by upregulating MHC-I expression

Westrich JA, Vermeer DW, Silva A, Bonney S, Berger JN, Cicchini L, Greer RO, Song JI, Raben D, Slansky JE, Lee JH, Spanos WC, Pyeon D. Oncogene. 2019; 38(46):7166-7180. PMID: 31417179.

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HIV-1 Impairment via UBE3A and HIV-1 Nef Interactions Utilizing the Ubiquitin Proteasome System

Pyeon D, Rojas VK, Price L, Kim SC, Singh M, Park IW. Viruses. 2019; 11: 1098. PMID: 31783587.

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2018

Human Papillomavirus 16 E7 Stabilizes APOBEC3A Protein by Inhibiting Cullin 2-Dependent Protein Degradation

Westrich JA, Warren CJ, Guo K, Liu C, Santiago ML, Pyeon D. Journal of Virology 2018; January 24. pii: JVI.01318-17. PMID: 29367246.

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DNA Tumor Virus Regulation of Host DNA Methylation and Its Implications for Immune Evasion and Oncogenesis

Kuss-Duerkop SK, Westrich JA, Pyeon D. Viruses 2018; 10(2). pii: E82. doi: 10.3390/v10020082. PMID: 29438328.

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Methylated genomic loci encoding microRNA as a biomarker panel in tissue and saliva for head and neck squamous cell carcinoma

Cao Y, Green K, Quattlebaum S, Milam B, Lu L, Gao D, He H, Li N, Gao L, Hall FK, Whinery M, Handley E, Ma Y, Xu T, Jin F, Xiao J, Wei M, Smith D, Bornstein S, Gross N, Pyeon D, Song JI, Lu SL. Clinical Epigenetics 2018; 10:43. PMID: 29636832.

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2017

Evasion of host immune defenses by human papillomavirus

Westrich JA, Warren CJ, Pyeon D. Virus Research. 2017; 231:21-33. PMID: 27890631.

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High-Risk Human Papillomavirus E7 Alters Host DNA Methylome and Represses HLA-E Expression in Human Keratinocytes

Cicchini L, Blumhagen RZ, Westrich JA, Myers ME, Warren CJ, Siska C, Raben D, Kechris KJ, Pyeon D. Scientific Report, 2017 Jun16;7(1):3633. PMID: 28623356.

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Roles of APOBEC3A and APOBEC3B in Human Papillomavirus Infection and Disease Progression

Warren CJ, Westrich JA, Doorslaer KV, Pyeon D. Viruses. 2017; Aug 21;9(8). pii: E233. doi: 10.3390/v9080233. PMID: 28825669. (One of the highest-scoring outputs from this source, #4 of 1,295)

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2016

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Klionsky DJ, et al. Autophagy. 2016;12(1):1-222. PubMed PMID: 26799652.

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Suppression of Antitumor Immune Responses by Human Papillomavirus through Epigenetic Downregulation of CXCL14

Cicchini L, Westrich JA, Xu T, Vermeer DW, Berger JN, Clambey ET, Lee D, Song JI, Lambert PF, Greer RO, Lee JH, Pyeon D. mBio, 2016; 7(3): e00270-16. PMID: 27143385.

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Function of ubiquitin (Ub) specific protease 15 (USP15) in HIV-1 replication and viral protein degradation

Pyeon D, Timani KA, Gulraiz F, Park IW. Virus Research, 2016. pii: S0168-1702(16)30091-0. PMID: 27460547.

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2015

APOBEC3A functions as a restriction factor of human papillomavirus

Warren CJ, Xu T, Guo K, Griffin LM, Westrich JA, Lee D, Lambert PF, Santiago ML, Pyeon D. Journal of Virology, 2015; 89(1):688-702. PMID: 25355878.

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Interaction between Nef and INI1/SMARCB1 augments replicability of HIV-1 in resting human peripheral blood mononuclear cells

Pyeon D*, Park IW*. Archives of Virology, 2015; 160(3):727-37. PMID: 25559666. (*Co-correspondence)

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Molecular transitions from papillomavirus infection to cervical precancer and cancer: Role of stromal estrogen receptor signaling

den Boon JA*, Pyeon D*, Wang SS, Horswill M, Schiffman M, Sherman M, Zuna RE, Wang Z, Hewitt SM, Pearson R, Schott M, Chung L, He Q, Lambert PF, Walker J, Newton MA, Wentzensen N, Ahlquist P. Proceedings of National Academy of Science USA, 2015; 112(25):E3255-64. PMID: 26056290. (*Equal contribution) (Recommended in F1000Prime)

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Comparative molecular genetic analysis of simian and human HIV-1 integrase interactor INI1/SMARCB1/SNF5

Pyeon D*, Price L, Park IW*. Archives of Virology, 2015 September 8. PMID: 26350979. (*Co-correspondence)

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Role of the host restriction factor APOBEC3 on papillomavirus evolution

Warren CJ, Van Doorslaer K, Pandey A, Espinosa JM, Pyeon D. Virus Evolution, 2015; 1 (1) vev015. PMID: 27570633.

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APOBEC3 in papillomavirus restriction, evolution and cancer progression

Warren CJ, Pyeon D. Oncotarget, 2015 Nov 24;6(37):39385-6. PMID: 26574726.

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2014

Human keratinocyte cultures in the investigation of early steps of human papillomavirus infection

Griffin LM, Cicchini L, Xu T, Pyeon D. Methods in Molecular Biology, 2014; 1195:219-38. PMID: 24281871.

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The antiviral restriction factors IFITM1, 2 and 3 do not inhibit infection of human papillomavirus, cytomegalovirus and adenovirus

Warren CJ, Griffin LM, Little AS, Huang IC, Farzan M, Pyeon D. PLoS One, 2014; 9(5):e96579. PMID: 24827144.

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2013

Human papillomavirus infection is inhibited by host autophagy in primary human keratinocytes

Griffin LM, Cicchini L, Pyeon D. Virology, 2013; 437:12-19. PMID: 23290079. (Editor's Selection 2013: one of 12 best publications in 2013)

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Inhibition of nuclear factor-kappa B activation decreases survival of Mycobacterium tuberculosis in human macrophages

Bai X, Feldman NE, Chmura K, Ovrutsky AR, Su WL, Griffin L, Pyeon D, McGibney MT, Strand MJ, Numata M, Murakami S, Gaido L, Honda JR, Kinney WH, Oberley-Deegan RE, Voelker DR, Ordway DJ, Chan ED. PLoS One, 2013; 8(4):e61925. PMID: 23634218.

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2012

Orphan nuclear receptor PNR/NR2E3 stimulates p53 functions by enhancing p53 acetylation

Wen Z, Pyeon D, Wang Y, Lambert PF, Xu W, Ahlquist P. Molecular and Cellular Biology, 2012; 32:26-35. PMID: 22025681.

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Novel Antivirals Inhibit Early Steps in HPV Infection

*Huang HS, *Pyeon D, Pearce SM, Lank SM, Griffin LM, Ahlquist P, Lambert PF. Antiviral Research, 2012; 93:280-7. PMID: 22197636. (*Equal contribution)

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2009

Establishment of human papillomavirus infection requires cell cycle progression

Pyeon D, Pearce SM, Lank SM, Ahlquist PG, Lambert PF. PLoS Pathogens, 2009; 5:e1000318. PMID: 19247434.

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2007

Fundamental differences in cell cycle deregulation in human papillomavirus-positive and human papillomavirus-negative head/neck and cervical cancers

Pyeon D, Newton MA, Lambert PF, den Boon JA, Sengupta S, Marsit CJ, Woodworth CD, Connor JP, Haugen TH, Smith EM, Kelsey KT, Turek LP, Ahlquist P. Cancer Research, 2007; 67:4605-4619. PMID: 17510386.

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2005

Production of infectious human papillomavirus independently of viral replication and epithelial cell differentiation

Pyeon D, Lambert PF, Ahlquist P. Proceedings of National Academy of Science USA, 2005; 102: 9311-9316. PMID: 15958530.

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2000

Prostaglandin E(2) increases bovine leukemia virus tax and pol mRNA levels via cyclooxygenase 2: regulation by interleukin-2, interleukin-10, and bovine leukemia virus

Pyeon D, Diaz FJ, Splitter, GA. Journal of Virology, 2000; 74:5740-5745. PMID: 10823885.

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1999

Regulation of interleukin-2 and -10 on bovine leukemia virus tax and pol mRNA expression

Pyeon D, Splitter GA. Journal of Virology, 1999; 73:8427-8434. PMID: 10482594.

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1998

Interleukin-12 p40 mRNA expression in bovine leukemia virus-infected animals: increase in alymphocytosis but decrease in persistent lymphocytosis

Pyeon D, Splitter GA. Journal of Virology, 1998; 72:6917-6921. PMID: 9658146.

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1996

Increased interleukin-10 mRNA expression in tumor bearing or persistently lymphocytotic animals infected with bovine leukemia virus

Pyeon D, O Reilly KL, Splitter GA. Journal of Virology, 1996; 70:5706-5710. PMID: 8764093

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